Assalamualaikum wr,wb
Embryo freezing is a procedure that allows embryos to be preserved for latter use. The first successful pregnancy resulting from freezing a woman's healthy embryos was in the 1980s.
Embryo freezing is a procedure that allows embryos to be preserved for latter use. The first successful pregnancy resulting from freezing a woman's healthy embryos was in the 1980s.
The embryos may be stored to enable a future pregnancy, to donate to others, for medical research or for training purposes.
The process to begins by using hormones and other medication stop stimulate the production of potentially fertile eggs. The eggs are then extracted from the woman's ovaries to either be fertilized in a lab or frozen for later use.
Successful fertilization may lead to at least one healthy embryo, which can then be transferred to the woman's womb or uterus. Hopefully, the embryo will develop and the woman can carry the developing infant through pregnancy to a live birth.
Since fertilization often results in more than one embryo, the remaining embryos can be preserved through freezing.
What is an embryo, and how is one created?
According to the Oxford Living Dictionaries, an embryo is "a human offspring during the period from approximately the second to the eighth week after fertilization."
Before freezing can take place, suitable embryos have to be created. To create an embryo in the laboratory, the egg must first be harvested and fertilized.
First, the woman will be given hormones to make sure she ovulates correctly. She is then given fertility medications to increase the number of egg she produces.
If the woman wishes to become pregnant at once, in vitro fertilization (IVF) or intra-cytoplasmic sperm injection (ICSI) may used to fertilized the egg.
During the process of IVF, the egg are exposed to sperm and mixture is cultured in laboratory. Fertilization may take 16 to 20 hours. The fertilized egg are called embryos.
An embryologist will monitor the development of the embryos over the next 6 days, after which a suitable embryo may be chosen for implantation.
In ICSI, once the egg have been extracted, a single sperm is injected directly into an egg. This may be done if there is a problem with the sperm or if past attempts at IVF have been unsuccessful.
How is an embryos frozen?
The main goal of embryos freezing is to preserve the embryo for later use. The biggest is the water within the cells. When water freezes, crystals can form. This expansion can burst the cell, causing it to die.
To prevent this happening, the water in the embryo's cell is replaced with a protective substance called a cryoprotectant. The embryos are left to incubate in increasing levels of cryoprotectant before they are frozen.
Once most of the water has been removed, the embryo is cooled to its preservation state through one of two methods of embryo Freezing.
Successful fertilization may lead to at least one healthy embryo, which can then be transferred to the woman's womb or uterus. Hopefully, the embryo will develop and the woman can carry the developing infant through pregnancy to a live birth.
Since fertilization often results in more than one embryo, the remaining embryos can be preserved through freezing.
What is an embryo, and how is one created?
Before freezing can take place, suitable embryos have to be created. To create an embryo in the laboratory, the egg must first be harvested and fertilized.
First, the woman will be given hormones to make sure she ovulates correctly. She is then given fertility medications to increase the number of egg she produces.
If the woman wishes to become pregnant at once, in vitro fertilization (IVF) or intra-cytoplasmic sperm injection (ICSI) may used to fertilized the egg.
During the process of IVF, the egg are exposed to sperm and mixture is cultured in laboratory. Fertilization may take 16 to 20 hours. The fertilized egg are called embryos.
An embryologist will monitor the development of the embryos over the next 6 days, after which a suitable embryo may be chosen for implantation.
In ICSI, once the egg have been extracted, a single sperm is injected directly into an egg. This may be done if there is a problem with the sperm or if past attempts at IVF have been unsuccessful.
How is an embryos frozen?
The main goal of embryos freezing is to preserve the embryo for later use. The biggest is the water within the cells. When water freezes, crystals can form. This expansion can burst the cell, causing it to die.
To prevent this happening, the water in the embryo's cell is replaced with a protective substance called a cryoprotectant. The embryos are left to incubate in increasing levels of cryoprotectant before they are frozen.
Once most of the water has been removed, the embryo is cooled to its preservation state through one of two methods of embryo Freezing.
- Slow freezing : this involves protecting the embryos from damage in sealed tubes and then slowly lowering the temperature in the tubes. This prevents the embryo cells from aging and becoming damaged. Embryos can last much longer in their frozen state than in their state. However, slow freezing is time-consuming, and it requires machinery.
- Vitrification : In this process, the cryoprotected embryos are frozen so quickly that the water molecules in the embryos do not have a time to from ice crystals. This helps to protect the embryos and to increase their survival rate during thawing.
After freezing, the embryos are store in liquid nitrogen until they are needed for future use.
Next to article.......
Success rate of thawing frozen embryos
The process of thawing an embryo is relatively successful. some research has indicated the embryos frozen through vitrification have a better chance of survival, both at the freezing stage and during thawing.
How long can embryos be frozen for?
A study posted in The International Journal of Reproductive Medicine looked at the result of over 1,000 cases of embryo transfer using either fresh or frozen embryos.
The result found no statistical different between using fresh and frozen embryos could also be used for additional embryo transfers in the future while fresh embryos could not.
Who is embryo freezing for?
Embryo freezing can be used by any woman, but there are certain group who may find it more beneficial than others.
These include women with genetic disorders of ovarian sensitivities, those who are during due to undergo chemotherapy, and those who take medications that affect fertility.
Women who are approaching advanced reproductive age and are not ready children yet may also benefit from freezing embryos for later use.
"Freeze-all" cycles
in a "Freeze-all" cycles, the embryo is extracted from a woman's body to be frozen for storage. This procedure may be offered to women who have a higher risk of ovarian stimulation syndrome. This rare and potentially dangerous condition happens when a woman is receiving stimulating hormones to increase egg production.
There are ways to reduce the change of developing this condition. for example, doctor may freeze the embryos and transfer them when the woman's ovaries are no longer stimulated. Woman who are going to receive a medical treatment that may affect their ovaries, such as chemoterapy, may choose to store their embryos.
Sometimes, a "Freeze-all" cycle is used to test an embryo for a genetic disorder. This involves removing a few strands of DNA from the embryo and testing their chromosomes. Embryos with a standard set of chromosomes are more likely to have a successful implant. Pre-screening can ensure that future offspring have a lower chance of developing genetic diseases.
Superb. I really enjoyed very much with this article here. Really it is an amazing article I had ever read. I hope it will help a lot for all. Thank you so much for this amazing posts and please keep update like this excellent article.thank you for sharing such a great blog with us. expecting for your.
ReplyDeleteBest IVF Centre in noida with highest success rate
Best embryo freezing treatment in noida